Product Details:
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Name: | NDSB 221 | Cas No: | 160788-56-7 |
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Application: | Biochemical Reagents | Purity: | 99% |
Classification: | In Vitro Diagnostic Reagents | Form: | Solid |
Color: | White | Samples: | Available |
Package: | 1kg/5kg/25kg | Transport: | Courier/Air/Sea |
Highlight: | CAS 160788-56-7 NDSB,99% 221 3-(1-Methylpiperidinio)-1-Propanesulfonate |
CAS 160788-56-7 NDSB 221 3-(1-Methylpiperidinio)-1-propanesulfonate
Basic information |
Product Name: | NDSB 221 |
CAS: | 160788-56-7 |
MF: | C9H19NO3S |
MW: | 221.32 |
Mol File: | 160788-56-7.mol |
solubility: | H2O: soluble50mg/mL, clear, colorless |
Color: | White |
Form: | Solid |
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Usage And Synthesis |
Description: | NDSB 221 is a nondetergent sulfobetaine that has been found to improve unfolding reversibility. |
Application: |
NDSB 221 has been used in a study to identify a novel ligand binding site in phosphoserine phosphatase from Thermococcus onnurineus. It has also been used in a study to investigate its effects on acidic fibroblast growth factor (aFGF). Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification. The typical usage concentration is 0.5 - 2.0 M. |
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