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Product Details:
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| Name: | 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid | Cas No: | 16052-06-5 |
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| Application: | Molecular Biology, BioReagent | Purity: | 99.5% |
| Classification: | Biological Buffer | Form: | Crystalline Powder |
| Color: | White | Samples: | Available |
| Package: | 1kg/5kg/25kg | Transport: | Courier/Air/Sea |
| High Light: | Biological Good's Buffer,EPPS Good's Buffer,CAS 16052-06-5 |
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HEPPS EPPS Buffer CAS 16052-06-5 Biological Buffers Bioreagent Good's Buffer
HEPPS (EPPS) is a buffering agent used in biology and biochemistry. The pKa of HEPPS is 8.00. It is ones of Good's buffers.
Research on mice with Alzheimer's disease-like amyloid beta plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice.HEPPS was reported to dissociate amyloid beta oligomers in patients' plasma samples enabling blood diagnosis of Alzheimer's disease
| EPPS Basic information |
| Product Name: | EPPS |
| Synonyms: | HEPPS(EPPS);4-(2-Hydroxyethyl)pi;HEPE;3-[4-(2-HYDROXYETHYL)-1-PIPERAZINE]PROPANESULFONIC ACID;3-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]PROPANESULFONIC ACID;N-(2-HYDROXYETHYL)-N'-(3-SULFOPROPYL)-PIPERAZINE;N-[2-HYDROXYETHYL]PIPERAZINE-N'-[3-PROPANESULFONIC ACID];N-2-HYDROXYETHYLPIPERAZINE-N'-3-PROPANESULPHONIC ACID |
| CAS: | 16052-06-5 |
| MF: | C9H20N2O4S |
| MW: | 252.33 |
| EINECS: | 240-198-8 |
| Product Categories: | Pharmaceutical Intermediates;Miscellaneous Biochemicals;Biochemistry;Good's Buffers;buffer |
| Mol File: | 16052-06-5.mol |
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| EPPS Chemical Properties |
| Melting point | 237-239 °C(lit.) |
| density | 1.2684 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Powder/Solid |
| color | White |
| PH | 5.0-6.5 (25℃, 0.1M in H2O) |
| PH Range | 7.3 - 8.7 |
| pka | 8.0(at 25℃) |
| Water Solubility | Soluble in water. 25.2 g/L (20°C) |
| λmax | λ: 260 nm Amax: 0.055 λ: 280 nm Amax: 0.045 |
| BRN | 3957385 |
| CAS DataBase Reference | 16052-06-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)- (16052-06-5) |
| EPPS Usage And Synthesis |
| Chemical Properties | white crystalline powder |
| Uses | EPPS is a commonly used Good?s buffer. It is often used as separator in ultrathin isoelectric focusing gels and enhances the resolution of phosphoglucomutase. It is used as a buffering agent in biology and biochemistry. |
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