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CAS 26305-03-3 Pepstatin A

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CAS 26305-03-3 Pepstatin A

CAS 26305-03-3 Pepstatin A
CAS 26305-03-3 Pepstatin A CAS 26305-03-3 Pepstatin A CAS 26305-03-3 Pepstatin A

Large Image :  CAS 26305-03-3 Pepstatin A

Product Details:
Place of Origin: China
Brand Name: YunbangPharm
Certification: ISO9001/SGS
Model Number: YB224
Payment & Shipping Terms:
Minimum Order Quantity: To Be Negotiated
Price: To Be Negotiated
Packaging Details: 1g 10g 100g
Delivery Time: 3-7 Working Days
Payment Terms: L/C, D/A, D/P, T/T, Western Union

CAS 26305-03-3 Pepstatin A

Description
Name: Pepstatin A CAS: 26305-03-3
Form: Solid Application(s): Biochemistry Reagent
Storage Temp.: 2-8°C
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Pepstatin A CAS 26305-03-3

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CAS 26305-03-3 Pepstatin A

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CAS 26305-03-3

CAS 26305-03-3 Pepstatin A

 

Product Name: Pepstatin
Synonyms: ahpatininc;pepsininhibitors735a;procidins735a;PEPSTATIN;PEPSTATIN A;X-VAL-VAL-STATYL-ALA-STATIN;(3S,4S)-4-AMINO-3-HYDROXY-6-METHYL-HEPTANOIC ACID;AHMHA ISOVALERYL-L-VAL-L-VAL-AHMHA-L-ALA-STA
CAS: 26305-03-3
MF: C34H63N5O9
MW: 685.89
EINECS: 247-600-0

 

Melting point 233 °C (dec.)(lit.)
alpha D27 -90.3° (c = 0.288 in methanol)
Boiling point 695.91°C (rough estimate)
density 1.1340 (rough estimate)
refractive index 1.7500 (estimate)
storage temp. 2-8°C
solubility 10% acetic acid in methanol: 1 mg/mL
form White solid
pka 4.17±0.10(Predicted)
color Colorless needles

 

 

General description

Pepstatin A is a naturally occurring chemotactic peptide and inhibitor of aspartic proteases that was initially isolated from culture filtrates of various Actinomycetes species, with the initial name simply of “pepstatin”. This name was later modified to “pepstatin A” to distinguish the original pepstatin from later derivatives. Pepstatin A notably contains the unusual amino acid 4-amino-hydroxy-6-methylheptanoic acid (AHMHA), which is known also as statine. The amino acid sequence of pepstatin A is N-Isovaleryl-L-Valyl-L-Valyl-AHMHA-L-Alanyl-AHMHA.

Application

Can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes. For this application, the working concentration is typically between 1-10 μM.

 

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