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Product Details:
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| Name: | Guanidine Thiocyanate | CAS: | 593-84-0 |
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| Form: | White Crystalline Powder | Odor: | Odorless |
| Application: | Molecular Biology, BioReagent | Solubility: | Water: 100 Mg/mL, Clear, Colorless |
| Highlight: | CAS 593-84-0 Guanidine Thiocyanate,Guanidine Thiocyanate IVD Reagents,Molecular Grade Guanidine Thiocyanate |
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Guanidine thiocyanate CAS 593-84-0 In Vitro Diagnostic Reagents Molecular Grade
| Product Name: | Guanidine thiocyanate |
| Synonym(s): | Guanidinium rhodanide |
| CAS: | 593-84-0 |
| MF: | CH5N3.CHNS |
| MW: | 118.16 |
| EINECS: | 209-812-1 |
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| Guanidine thiocyanate Chemical Properties |
| Melting point | 120-122 °C(lit.) |
| density | 1.103 g/mL at 20 °C |
| refractive index | n |
| storage temp. | 20-25°C |
| solubility | H2O: 6 M at 20 °C, clear, colorless |
| form | Crystals or Crystalline Powder |
| Specific Gravity | 1.152 |
| color | White or colorless |
| Odor | Odorless |
| PH | 4.8-6.0 (1420g/l, H2O, 20℃)(saturated solution) |
| PH Range | 4.8 - 6.0 |
| Water Solubility | Soluble in water and ethanol |
| Sensitive | Light Sensitive |
| BRN | 3563461 |
| Stability: | Stability Stable, but light sensitive. Incompatible with acids (contact releases very toxic gas), strong oxidising agents. |
| InChIKey | ZJYYHGLJYGJLLN-UHFFFAOYSA-N |
| CAS DataBase Reference | 593-84-0(CAS DataBase Reference) |
| EPA Substance Registry System | Thiocyanic acid, compd. with guanidine (1:1) (593-84-0) |
| Guanidine thiocyanate Usage And Synthesis |
| Description | Guanidine thiocyanate is one of the cheapest and easiest to prepare of the guanidine salts. Guanidine Thiocyanate is an ultrapure, molecular biology grade reagent. It is free of detectable nuclease and protease activity and is a strong protein denaturant, as both the guanidinium cation and the thiocyanate anion are chaotropic agents. It is provided in one bottle containing 500 g. It is recommended for isolation of RNA, especially for tissues such as pancreas with high levels of RNase activity. In solution, it is known as guanidinium thiocyanate. Guanidine Thiocyanate is thoroughly tested for contaminating nonspecific endonuclease, exonuclease, and RNase activity. |
| Chemical Properties | White cryst.powder |
| Uses | Potent protein denaturant used in isolation of intact DNA, RNA. |
| Uses | Guanidine thiocyanate is a useful tool for RNA isolation and protein solubilization. It is involved in the quantification of mRNA from hepatocytes. It acts as a medium for blood smaple lystae in order to maintain the integrity of nucleic acid. It is a chaotropic agent, mainly involved in the extraction of DNA and RNA. It is utilized to deactivate the influenza virus. |
| Uses | Guanidine thiocyanate has been used as a component of the stabilization buffer for RNA lysis. It can be used for deactivation of endogenous RNases leading to denaturation of nucleoprotein complexes. It is also suitable for denaturation of macromolecules such as nucleic acids and proteins and for RNA isolation. |
| General Description | Guanidine thiocyanate is chaotropic salts which lyse cells and along with nuclease binding matrix it is also seen to inhibit nuclease activity during extraction of DNA. It works as a strong RNase inhibitor in extraction buffers. |
Contact Person: Maggie Ma
Tel: +0086 188 7414 9531
