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CAS 96-82-2 Lactobionic Acid,
ISO9001 D-Gluconic Acid Intermediates
Lactobionic acid CAS 96-82-2 Glycoside D-Gluconic acid intermediates
|Lactobionic acid Basic information
|4-O-BETA-D-GALACTOPYRANOSYL-D-GLUCONIC ACID;LACTOBIONIC ACID;4-O-β-D-Galactopyranosyl-D-gluconic acid;LACTOBIONIC ACID FREE ACID;LACTOBIONIC ACID 97%;4-[β-D-Galactosido]-D-gluconic acid;Lactobionic Acid (mixture of Acid form and Lactone form);D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl-
|Lactobionic acid Chemical Properties
|22.8 º (c=10, H2O)
|410.75°C (rough estimate)
|1.4662 (rough estimate)
|26 ° (C=8.8, H2O)
|Inert atmosphere,Room Temperature
|10 g/100 mL
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|[α]20/D +25°, c = 10 in H2O
|10 g/100 mL
|CAS DataBase Reference
|96-82-2(CAS DataBase Reference)
|Lactobionic acid Usage And Synthesis
|Lactobionic acid (C12H22O12) is a disaccharide obtained from the oxidation of lactose. Chemically, Lactobionic acid is made up of a galactose moiety that is bonded to a gluconic acid molecule through an ether-like bond. The compound can be dehydrated to a lactone. Lactobionic acid is widely used in the chemical, food and pharmaceutical industries due to its chelating, emulsifying, humectant and chelating properties. Lactobionic acid and its constituent salts are essential as food additives due to excellent solubility, good taste, and health-promoting aspects. The compound may also be essential in the synthesis of targetable and biocompatible drug delivery systems.
|Lactobionic acid has a molecular weight of 358.296 g/mol and a monoisotopic mass of 358.111 g/mol, which is also its exact mass. The compound has a heavy atom count of 24.
Lactobionic acid has a melting point of 113-118°C and a boiling point of about 410.75°C. It is a white to off-white powder with a solubility of 10 g/100 mL in water and a density of about 1.4662. It is also slightly soluble in anhydrous methanol and ethanol.
Lactobionic acid is hygroscopic, and it has a good water retention potential hence its applicability to cosmetic products. The compound and its constituent mineral salts (Ca, Na, and K lactobionate) are produced commercially for medical and industrial applications and in some cases for research purposes.
|The selective transformation of lactose into Lactobionic acid entails the oxidation of the radical aldehyde category of glucose on the lactose molecule to the carboxylic classification. The production of Lactobionic acid entails various processes which may include enzymatic synthesis, microbial production, biocatalytic oxidation, electrochemical oxidation and heterogeneous catalytic oxidation.
|Extraction and Purification
|To enhance the productive capacity of Lactobionic acid, the enzymatic reaction can be cut off after several hours of activity and the unchanged substrates can be re-injected into the cycle after the elimination of useful products. The effective process of separation is through liquid chromatography particularly because the recovered species are pure.
Exposing the solution made of lactobionate ions through a sequence of ion-transfer resins produces a pure solution of Lactobionic acid with minimal amounts of calcium ions. Different techniques such as crystallization, evaporation, electrodialysis and ethanol precipitation can be employed to obtain Lactobionic acid.
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