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EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT

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EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT

EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT
EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT

Large Image :  EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT

Product Details:
Place of Origin: China
Brand Name: YunbangPharm
Certification: ISO9001
Model Number: YB041
Payment & Shipping Terms:
Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1kg/Bottle, 5-25kg/Drum
Delivery Time: 5-8 working days
Payment Terms: L/C, D/A, D/P, T/T, Western Union
Supply Ability: 200kg

EGTA Biological Buffers CAS 67-42-5 Ebonta Egtazic Acid Egtazic AEGT

Description
Name: EGTA Cas No: 67-42-5
Application: Bioreagent Purity: 98%
Classification: Biological Buffer Form: Powder
Color: White To Slightly Off-white Package: 1kg/5kg/25kg
Transport: Courier/Air/Sea Samples: Available
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CAS 67-42-5

EGTA CAS 67-42-5 ethylene glycol bis(2-aminoethyl)tetraacetic acid

 

EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibited the substrate adherence capacity of inflammatory macrophages[1][2].

 

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Basic information
Product
Name:
Ethylenebis(oxyethylenenitrilo)tetraacetic acid
Synonyms: 3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID;1,2-bis(2-dicarboxymethylaminoethoxy)ethane;12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-9-dioxa-3;6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-;9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-6;ebonta;ethylenedioxybis(ethyleneamino)tetraaceticacid;ETHYLENE GLYCOL BIS-(BETA-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC
CAS: 67-42-5
MF: C14H24N2O10
MW: 380.35
EINECS: 200-651-2
Product Categories: Analytical Chemistry;Chelating Reagents;Complexones;EDTA Analogs
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Structure
 
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Chemical Properties
Melting point 241 °C (dec.)(lit.)
Boiling point 507.99°C (rough estimate)
density 1.2838 (rough estimate)
refractive index 1.4590 (estimate)
storage temp. room temp
solubility 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
pka 1.47±0.10(Predicted)
form Crystalline Powder
color White
Water Solubility slightly soluble
Merck 14,3529
BRN 1717370
CAS DataBase Reference 67-42-5(CAS DataBase Reference)
EPA Substance
Registry System
Ethylenebis(oxyethylenenitrilo)tetraacetic acid (67-42-5)
 
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-36-26
WGK Germany 2
RTECS AH3760000
TSCA Yes
HS Code 29225000
Toxicity LD50 orally in Rabbit: 3587 mg/kg
 
 
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Usage And Synthesis
Description

Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium.

Chemical
Properties
White to slightly off-white powder
Uses Pharmaceutic aid. EGTA.
Uses Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, which help to determine calcium in the presence of magnesium. It can be used experimentally for treating animals possessing cerium poisoning. It is useful in the separation of thorium from monazite. It also acts as a buffer and is used in protein purification.
Uses A chelating agent useful for the determination of calcium in the presence of magnesium.
Definition ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
Biological Activity Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.
Safety Profile Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also GLYCOL ETHERS.
Purification Methods Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.]

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