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MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide

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MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide

MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide
MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide

Large Image :  MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide

Product Details:
Place of Origin: China
Brand Name: YunbangPharm
Certification: ISO9001
Model Number: YB102
Payment & Shipping Terms:
Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1kg/Bottle, 5-25kg/Drum
Delivery Time: 5-8 working days
Payment Terms: L/C, D/A, D/P, T/T, Western Union
Supply Ability: 200kg

MTT CAS 298-93-1 Biological Stains 98% Thiazolyl Blue Tetrazolium Bromide

Description
Name: Thiazolyl Blue (MTT) Cas No: 298-93-1
MF: C18H16BrN5S Purity: 98%
Classification: Biological Stains Form: Powder
Color: Yellow To Orange Package: 1kg/5kg/25kg
Transport: Courier/Air/Sea
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CAS 298-93-1 Biological Stains

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MTT Biological Stains

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Thiazolyl Blue Tetrazolium Bromide

MTT CAS 298-93-1 Biological Stains Thiazolyl Blue 98%

 

Thiazolyl Blue Basic information
Product Name: Thiazolyl Blue
Synonyms: 2-(4,5-Dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazol-3-ium Bromide;Thiazolyl Blue Tetrazolium Bromide Vetec(TM) reagent grade, 98%;ACRYL/BIS 29:1 PREMIXED PWD ULTRA PURE;3-(4,5-Dimethyl-2-Thiazolyl)-2,5-Diphenyl;3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide;2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide;2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)-2h-tetrazolium Bromide;2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium Bromide
CAS: 298-93-1
MF: C18H16BrN5S
MW: 414.32
EINECS: 206-069-5
Thiazolyl Blue Structure
 
Thiazolyl Blue Chemical Properties
Melting point 195 °C (dec.) (lit.)
density 1.4886 (estimate)
storage temp. 2-8°C
solubility methanol: 5 mg/mL, clear
form powder
color Yellow to orange
Water Solubility Slightly soluble
λmax 378 nm, 242 nm
Sensitive Light Sensitive
BRN 3825277
Stability: Hygroscopic
Biological Applications Cell viability assay; microbial growth assays; DNA quantification assays; tissue viability assays; detecting enzymes; measuring membrane potential; treating Alzheimer’s disease,asthma,cancer
InChIKey AZKSAVLVSZKNRD-UHFFFAOYSA-M
CAS DataBase Reference 298-93-1(CAS DataBase Reference)
EPA Substance Registry System 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (298-93-1)
 
Safety Information
Hazard Codes Xi,T,Xn
Risk Statements 46-68-36/37/38
Safety Statements 22-24/25-53-45-36/37-26
WGK Germany 3
RTECS XF8060000
F 3-8-10
TSCA Yes
HS Code 29341000
Hazardous Substances Data 298-93-1(Hazardous Substances Data)
 
Thiazolyl Blue Usage And Synthesis
Chemical Properties yellow crystalline powder
Uses Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation. MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent and for the detection of NAD. ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used. MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.
Definition ChEBI: Thiazolyl Blue is the bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium. It has a role as a dye and a colorimetric reagent. It contains a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.
General Description Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium) is a cell-permeable and positively charged colorimetric agent that is widely used to detect reductive metabolism in cells and to measure cell proliferation, cytotoxicity, and apoptosis. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Biochem/physiol Actions Cell permeable: yes
Purification Methods It is recrystallised by dissolving in MeOH containing a few drops of HBr and then adding dry Et2O to complete the crystallisation, wash the needles with Et2O and dry them in a vacuum desiccator over KOH. [Beyer & Pyl Chem Ber 87 1505 1954, Beilstein 27 III/IV 6045.]

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